BPB-0002_CIP Systems (Bio-Pharm)_Brochure_Rev3.0

Bio-Pharm

Clean-In-Place (CIP) Systems: Validatable Cleaning of Process Lines, Equipment and Vessels.

1 Tank System

2 Tank System

Sani-Matic Clean-In-Place (CIP) Systems are engineered to your specific plant application and utility requirements for effective and efficient process equipment cleaning. Sani-Matic's CIP design and sizing ensure sufficient flow and appropriate pressure to thoroughly remove residue, rinse effectively, shorten cycle times, reduce operating costs and promote worker safety. The CIP Systems meet cGMP and ASME BPE standards.

sanimatic.com

Sani-Matic Clean-In-Place (CIP) Systems are designed and supported to meet individual process requirements from programming to documentation and service.

Advantages • Complete Clean. Proper CIP design and sizing ensure the required time, chemical, flow and temperature are in place to thoroughly remove residue, while reducing cycle time and operating costs. • Validatable. Complete documentation available to comply with regulatory and validation requirements. Data acquisition and reporting capabilities are also available. • Programming and Controls. Sani-Matic controls are designed to optimize cycle times and reduce chemical and water use. Ethernet communications interface with individual process control systems for an integrated solution. • Service. Sani-Matic’s dedicated service team is available for full technical support during the start-up and after installation.

Industry Standard Compliance • FDA Current Good Manufacturing Practices (cGMP), CFR Title 21, Part 820 • Underwriters Laboratory (UL): Controls, Standard 508

• ANSI/ISA-88 (S88) Batch Control • Authorized to Provide Canadian Registration Numbers (CRN) • ASME BPE Standards

Features

1 Tank System • Single-use source of cleaning solution and rinse water • Low capital investment

2 Tank System • Single-use source of cleaning solution and rinse water • Stationary design • Once-through or recirculated • Decreased cycle time over single-tank design

• Portable or stationary design • Once-through or recirculated • Minimal space requirement

1 Tank Schematic

2 Tank Schematic

Pharma 1-Tank

Pharma Multi-Tank

CE

FE

CIP Return

CE

FE

CIP Return

TE

TE

CIP Supply

RO

WFI

CIP Supply

Drain

RO

WFI

Drain

Chemical Supply

Steam

Wash/Rinse

Steam

Wash Solution

Rinse

AIR

AIR

LE

LE

LE

CE PE

FE

CE PE

FE

TE

TE

Supply Pump

Supply Pump

Chemical Supply

Chemical Supply

Drain

Drain

Condensate Return

Condensate Return

Drain

Drain

sanimatic.com

System Automation Sani-Matic has designed, manufactured and supported thousands of CIP control systems with its in-house programmers and UL authorized panel shop. Advantages of Sani-Matic Controls • Experts. The Sani-Matic programming and automation team specializes in cleaning applications and provides proven expertise and customized strategies. • Automation Ease & Flexibility. Easy-to-understand Recipe Editor provides access to setpoints. Defined alarms reduce troubleshooting time. • Time, Water & Chemical Savings. Recipe optimization shortens cycle time and minimizes water and chemical use.

SaniTrend ® Cloud Reporting Software

Add SaniTrend ® Cloud Cleaning Reports (CR) software to your equipment to efficiently and automatically record and store critical data (e.g., temperature, conductivity). SaniTrend ® Cloud CR Insights+ records all critical data in easy-to-interpret cleaning records and additional insights like event logs, Overall Equipment Effectiveness (OEE) scoring, Preventive Maintenance (PM) Tracking, and more. The Insights+ edition also logs a full HMI Audit Trail and is 21 CFR Part 11 compliant for electronic records and signatures. Learn more at our website at sanimatic.com/sanitrendcloud/

Features

Standard • Allen-Bradley PLC and HMI • 40 customizable cleaning cycle recipes

• Ethernet communication • 316Lss wetted surfaces • UL listed, 304 stainless steel, NEMA 4X enclosure

Documentation

Standard • O peration and maintenance manuals • R ecommended spare parts (RSP) list

Optional • F unctional Specifications (FS) • C onfiguration Specification (CS) • Factory Acceptance Test (FAT) • Site Acceptance Test (SAT) • Installation and Operation Qualification (IQ/OQ) • T raceability matrix • Instrument data sheets

• Mechanical Bill of Materials (BOM) • Instrumentation calibration records • M aterial Test Reports (MTRs) • W eld maps and weld logs (including qualification and inspection records) • Inspection test results, reports and certificates • C omponent vendor documentation • A s-built General Assembly (GA) drawings • A s-built Process and Instrumentation Diagrams (P&ID) • A s-built electrical drawings

• B orescope Inspection Video • H ydrostatic test certificate • C leaning and passivation certificate • R iboflavin spray coverage test

BPB-0002.3

Cleaning Confidence. Repeatable results you can count on every time you clean your process parts and equipment. That’s Cleaning Confidence from Sani-Matic.

sanimatic.com

Sani-Matic, Inc.

(p) 800-356-3300

(f) 608-222-5348

Page 1 Page 2 Page 3 Page 4

www.sanimatic.com

Powered by